"My name is Frank Gibbes and I am a seven-year survivor of CML (Chronic Myloid) leukemia. I was diagnosed
on
June 5, 1997
– it was the day that changed my life. It was in my doctor’s office. My doctor
had sat me down and said, “Well, I’ve got some good news and I’ve got some bad
news. The blood counts look OK except for this one thing. Well, your white
cell count is a little high.” He told me that my white cell count was 350,000.
Then he told me that normally the white blood count would be about 15,000. I
realized that I was in some kind of trouble. I still didn’t really understand
it until he told me. “I’ve taken the liberty of calling your father and he is
on his way over here.” I knew as soon as he told me that he had called my dad
I knew that I was in some trouble. I went from the doctor’s office to the hospital
and spent three days there undergoing various tests, taking a lot of medicine.
After three days they let me out, which began a whirlwind of research, and traveling
and information gathering to determine where the best place to have a bone marrow
transplant was. Eventually we settled on
Columbia
,
SC
and in October of ’97, I went to
Columbia
SC
and began my treatment. Three days of high-dose total-body radiation and five
days of high dose chemotherapy by the end of which I was completely worn out and
could barely stand. It was only after that they gave me the bone marrow transplant
transfusion. As opposed to transplanting a heart or another organ, it’s really
just basically a bag of blood. It takes about two and a half minutes for it to
run into your body and you just wait and hope that it grows. In my case, it tried
to grow for about a year and a half and then it was ultimately determined that
my bone marrow transplant had failed. We started to look at more less likely options
for some type of cure - one option was a second bone marrow transplant but the
odds were so bad on surviving a second bone marrow transplant that we decided
to look elsewhere. We chose this clinical study, a clinical trail, that involved
taking more blood out of my brother, manipulating it genetically, then putting
it back in me in the hopes it would allow the bone marrow that my brother had
given me to grow the way it was supposed to. I went through four treatments where
I would to down to the treatment center in
Columbia
- they would infuse me with the genetically changed cells, then I would go
home, and they would just keep tabs on me. About that time, a little known study
was taking place on a drug that was known as Gleevec. It was actually called
STI-571 at the time. We heard about it because my doctor, my oncologist, had seen
a little blip off of an Internet site that he frequented regarding oncological
things, I guess, and wanted us to look into it. It just so happened the study
was taking place at the University of Texas Medical Center - the MD Anderson Cancer
Center. We called, found out that I could get on the trial. I got down there
immediately to receive my treatment - my STI-571, which was just a pill, and be
monitored by the doctors there.
The end result was miraculous. 
The doctors found that pretty much everybody they gave the drug to… virtually
cured everyone. It wasn’t true with everybody, but it was true for a lot, and
it was true for me. I went in the first three months of being on the drug from having an 87%
leukemia count to a 12 % leukemia count, and it just went down from there. Eventually,
I graduated from law school and returned to
South Carolina
. Shortly thereafter, my wife and I, living in
Greenville
, received an invitation to an American Cancer Society gala over in
Spartanburg
. So we went to the Gala, and so we sat down at a table in the back and were
surrounded by American Cancer Society volunteers. They asked about my situation,
about the fact I had leukemia, and then someone spoke up and said, “Well, have
you heard about this new drug, this STI-571? –
it’s a miracle drug!” We looked at them and smiled and I said, “
Why, yes I’ve been on it for six months now.” From that point on, I’ve been involved with the American Cancer Society.
I’ve been involved as a volunteer, and been involved as a spokesperson, but the
wonderful part about it is, that without the American Cancer Society, I would
have never had that chance. As it turned out,
STI-571 was originally developed with a grant from the American Cancer Society.
Without that money, the drug that saved my life would not have been developed.”